As part of your aneuploidy screening program: Get second trimester screening performance for Down syndrome already in the first trimester

PerkinElmer is the only company that offers four CE-marked assays –PAPP-A, free hCGß, PlGF and AFP – for 1T screening of Down syndrome. Together these assays enable screening in the first trimester even in the absence of Nuchal Translucency (NT) measurement. In fact, recent studies show that maternal serum placental growth factor (PlGF) and alpha fetoprotein (AFP) measured together with the two established markers PAPP-A and free hCGß in the first trimester of pregnancy can be more effective than conventional 2T triple marker tests.

1T Quad is the first biochemistry-only screening protocol for Down syndrome in the first trimester

  • Supports strategies that include NIPT
  • Identifies risk in the first trimester rather than second trimester
  • Cost-effective use of resources

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