App Note

Research on neutralizing antibodies in autoimmune diseases

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Identifying potent biotherapeutics to address autoimmune diseases with an HTRF approach

Autoimmune diseases are associated with uncontrolled production of inflammatory cytokines that attack different parts of the body. Neutralizing monoclonal antibodies can be used to counter this phenomenon by disrupting intracellular signaling pathways. HTRF technology is effective for studying neutralizing antibodies and analyzing various parameters.

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  • Review TNFα and IL6 pathways
  • Discover the successful application of HTRF for studying anti-IL6R and anti-TNFα antibodies
  • See detailed experimental conditions and explanatory diagrams

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