Analytics Resource Center

Welcome to the PerkinElmer Informatics Analytics Resource Center featuring a gallery of interactive dashboards powered by TIBCO Spotfire.

For more information or technical assistance, you can contact us at
informatics.arc@perkinelmer.com

Application of AT-MAPP assay in assessing proteome-wide selectivity of covalent inhibitor ARS-1620
This Spotfire dashboard presents an activity-based cysteine profiling study of covalent inhibitor ARS-1620 to assess its proteome-wide selectivity. In the dashboard you can explore data from multiple levels interactively, including dynamic and dose-dependent quantitative changes in cysteine site and protein levels in response to drug treatment.


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Application of AT-MAPP assay in profiling covalent fragment targets
This Spotfire dashboard presents an activity-based cysteine profiling study of multiple covalent fragments to identify their cellular targets. In the dashboard you can explore data from multiple levels interactively, such as identifying the most significant hits and drilling down to review data on individual replicates.

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Application of AT-MAPP assay in mapping proteome-wide lysine hotspots

This Spotfire dashboard presents an activity-based hotspots profiling study to identify proteome-wide reactive lysine and other nucleophilic residues. In the dashboard you can explore data from multiple levels interactively, and track any site for its dose-dependent reactivity.

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Multiplexed proteomic profiling of innate immune antimicrobial response- Global Proteome
This Spotfire dashboard presents global proteome profiling of wild type and autophagy-deficient macrophages in response to infection with intracellular bacteria ( Shigella flexneri ). This resource contains dynamic genotype- and infection-dependent differences in host and pathogen proteins.




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Multiplexed proteomic profiling of innate immune antimicrobial response-Phosphorylation
This Spotfire dashboard presents phosphoproteome profiling of wild type and autophagy-deficient macrophages in response to infection with intracellular bacteria ( Shigella flexneri ). This resource contains dynamic genotype- and infection-dependent differences in host phosphoproteome.

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Multiplexed proteomic profiling of innate immune antimicrobial response-Ubiquitin
This Spotfire dashboard presents ubiquitinome profiling of wild type and autophagy-deficient macrophages in response to infection with intracellular bacteria (Shigella flexneri). This resource contains dynamic genotype- and infection-dependent differences in host KGG sites.

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Global phosphoproteome profiling of MuSK signaling
This Spotfire dashboard contains data for time-resolved and dose-dependent phosphoproteome profiling of the receptor tyrosine kinase MuSK signaling in myotubes. You can view the results of MuSK activation by agrin or MuSK agonist antibody (Ab #13) by individual proteins and phosphosites. Localization probabilities assigned by Ascore algorithm for each phosphorylation site are also provided.

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COVID -19 Clinical Trials Dashboard
This Spotfire dashboard tracks all the ongoing COVID-19 clinical trials. You can view the details by phase, recruitment status, search on a specific intervention or retrieve data by sponsor. Treatments and vaccines under investigation are listed as well.

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