Identification and characterization of novel positive allosteric modulators of the Dopamine D1 Receptor

Identifying therapeutic candidates for Schizophrenia through HTS

This Poster summarizes a study from the London Centre for Therapeutics Discovery investigating allosteric modulators of the Dopamine D1 receptor, in order to identify potential therapeutic candidates for the treatment of Schizophrenia.

Features

  • Methodology followed by the authors
  • Key results of the study (HTS performance and hit rates)
  • Conclusion suggesting the identification of a novel allosteric modulator

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